Although this is not applicable to Infinite Flight, it is interesting. Here’s a list of some permanently prohibited areas you’ll find in airspace around the United States.
Thurmont, Maryland, site of Presidential retreat Camp David (Prohibited Area 40 or P-40)
Amarillo, Texas, Pantex nuclear assembly plant (P-47)
Bush Ranch near Crawford, Texas (P-49)
Naval Submarine Base Kings Bay, Georgia (P-50)
Naval Base Kitsap, Washington (P-51)
Washington, D.C., U.S. Capitol, White House, and Naval Observatory (P-56); see other restrictions for information about all Active Prohibited Areas in the Washington D.C./Baltimore Flight Restricted Zone.
Bush compound near Kennebunkport, Maine (P-67)
Mount Vernon, Virginia, home of George Washington (P-73)
Boundary Waters Canoe Area Wilderness in northern Minnesota (P-204, 205, and 206)
You can find all of these prohibited areas marked on a VFR sectional chart, with information including the prohibited area number, altitude (MSL), time of use (in local), controlling agency, and communication frequency. Here’s an example of what to look for on a sectional chart.